The department of Microbiology is well equipped to teach and diagnose most of the infectious diseases prevalent in the society. The department offers diagnostic services to the hospital regarding bacteriology, mycobacteriology, virology, mycology, parasitology, immunology, serology and medical entomology. Special equipments such as inverted tissue culture microscope, anaerobic system, colony counter, electrophoresis, Automatic ELISA system, walk- in incubator, walk-in cooler, deep freezer, biosafety cabinet for mycobacteriology etc, fortify the diagnostic capabilities. The department also carries out bacteriological analysis of water, theatre sterility checks, in-house disinfectant testing and hospital environment surveillance.Since 2001, the department has upgraded as a postgraduate training centre and offers MD degree course in Microbiology.

The department is an active participant of the Revised National Tuberculosis Control Programme (RNTCP) and Prevention of Parent to Child Transmission of HIV (PPTCT) conducted by the Government of India. The diagnostic segment of the department participates regularly in the external quality control programmes. The department maintains a scientifically designed central animal house stocked with pedigreed animals of different species, for research.